⚠️ FOR RESEARCH PURPOSES ONLY — All compounds and data are for in vitro laboratory research and educational reference only. Not for human or animal use. Not evaluated by the FDA.
Research Library 28 Compounds

Research Peptide Blog Database

Peer-reviewed studies, clinical data, mechanism breakdowns, and molecular specifications — all in one place.

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Research Library Neuromodulatory Peptide

Delta Sleep-Inducing Peptide · Neuromodulator

DSIP

Delta sleep-inducing peptide. For in vitro research use only.

FormulaC35H48N10O15
Mol. Weight848.82 g/mol
CAS62568-57-4
SequenceTrp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
PubMed Indexed Research Use Only

Published Scientific Research

Peer-reviewed studies investigating DSIP sourced from PubMed-indexed journals for educational reference only.

Research Article PubMed

Delta sleep-inducing peptide.

European journal of anaesthesiology 2001
Pollard BJ, Pomfrett CJ et al.
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Literature Review PubMed

Delta sleep-inducing peptide (DSIP): a still unresolved riddle.

Journal of neurochemistry 2006
Kovalzon VM, Strekalova TV et al.

Delta sleep-inducing peptide (DSIP) was isolated from rabbit cerebral venous blood by Schoenenberger-Monnier group from Basel in 1977 and initially regarded as a candidate sleep-promoting factor. However, the link between DSIP and sleep has never...

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Literature Review PubMed

Delta-sleep-inducing peptide (DSIP): an update.

Peptides 1986
Graf MV, Kastin AJ et al.

The isolation and characterization of delta-sleep-inducing peptide (DSIP) achieved from 1963 to 1977 were reviewed in 1984. The first reports describing sleep as well as extra-sleep effects of DSIP also were included in that work....

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Literature Review PubMed

Delta-sleep-inducing peptide (DSIP): a review.

Neuroscience and biobehavioral reviews 1984
Graf MV, Kastin AJ et al.

Since the turn of the century, it has been postulated that humoral factors induce sleep. Many compounds were proposed as sleep-factors, but only two of the sleep-peptides have been purified to homogeneity and characterized, so...

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Clinical Trial PubMed

Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke.

Molecules (Basel, Switzerland) 2021
Tukhovskaya EA, Ismailova AM, Shaykhutdinova ER et al.

: Mutual effect of the preliminary and therapeutic intranasal treatment of SD rats with DSIP (8 days) on the outcome of focal stroke, induced with intraluminal middle cerebral occlusion (MCAO), was investigated. : The groups...

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Research Article PubMed

The effects of delta-sleep-inducing peptide (DSIP) on wakefulness and sleep patterns in the cat.

Brain research 1987
Susić V, Masirević G, Totić S et al.

The effect of a single injection of synthetic delta-sleep-inducing peptide (DSIP, 7 nmol/kg) into the lateral ventricle of 10 cats was investigated by monitoring the sleep-wake cycle during an 8 h period. A significant decrease...

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Research Article PubMed

Delta-sleep inducing peptide entrapment in the charged macroporous matrices.

Materials science & engineering. C, Materials for biological applications 2014
Sukhanova TV, Artyukhov AA, Gurevich YM et al.

Various biomolecules, for example proteins, peptides etc., entrapped in polymer matrices, impact interactions between matrix and cells, including stimulation of cell adhesion and proliferation. Delta-sleep inducing peptide (DSIP) possesses numerous beneficial properties, including its abilities...

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Research Article PubMed

Delta sleep-inducing peptide and its tetrapeptide analogue alleviate severity of metaphit seizures.

Pharmacology, biochemistry, and behavior 2004
Stanojlović O, Zivanović D, Mirković S et al.

The effects of delta sleep-inducing peptide (DSIP) and its tetrapeptide analogue, DSIP(1-4), on metaphit-induced audiogenic seizures were studied. Five groups of adult male Wistar rats were intraperitoneally treated with (1) saline, (2) metaphit, (3) DSIP,...

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Research Notice: All studies are presented for educational and informational purposes only. These compounds are for in vitro laboratory research use only (RUO). Not for human or animal use. Not evaluated or approved by the FDA.
Compound Information

Technical Specifications

🔬 Molecular Profile

TypeNeuromodulatory Peptide
ClassificationNaturally Occurring
CAS Number62568-57-4
Mol. Weight848.82 g/mol
SequenceTrp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
FormulaC35H48N10O15
OriginHypothalamus

🧊 Storage Requirements

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Lyophilized (powder) -20°C up to 2 years
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Reconstituted 2-8°C up to 30 days
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Working solution Use within 24 hours
Protect from light • Avoid repeated freeze-thaw cycles
Research Grade

Research-Grade DSIP

≥98% purity, third-party COA verified, lyophilized for stability. For in vitro laboratory research use only.

⚠️ Research Use Only. Not for human or animal use. Not evaluated or approved by the FDA.

⚠️ Important Research Notice

All compounds listed are intended exclusively for in vitro laboratory research by qualified professionals. Not for human or animal consumption. Not approved by the FDA for any diagnostic, therapeutic, or clinical purpose. All research findings are sourced from peer-reviewed journals for educational reference only. Not to be interpreted as medical advice or product claims.