⚠️ FOR RESEARCH PURPOSES ONLY — All compounds and data are for in vitro laboratory research and educational reference only. Not for human or animal use. Not evaluated by the FDA.
Research Library 28 Compounds

Research Peptide Blog Database

Peer-reviewed studies, clinical data, mechanism breakdowns, and molecular specifications — all in one place.

🔍
Research Library Nuclear Receptor Agonist

ERR Agonist · Exercise Mimetic Compound

SLU-PP-332

ERR agonist. For in vitro research use only.

FormulaC28H29FN4O3S
Mol. Weight524.62 g/mol
PubMed Indexed Research Use Only

Published Scientific Research

Peer-reviewed studies investigating SLU-PP-332 sourced from PubMed-indexed journals for educational reference only.

In Vivo Study PubMed

A Synthetic ERR Agonist Alleviates Metabolic Syndrome.

The Journal of pharmacology and experimental therapeutics 2024
Billon C, Schoepke E, Avdagic A et al.

Physical exercise induces physiologic adaptations and is effective at reducing the risk of premature death from all causes. Pharmacological exercise mimetics may be effective in the treatment of a range of diseases including obesity and...

View Full Study on PubMed →
In Vitro Study PubMed

Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.

ACS chemical biology 2023
Billon C, Sitaula S, Banerjee S et al.

Repetitive physical exercise induces physiological adaptations in skeletal muscle that improves exercise performance and is effective for the prevention and treatment of several diseases. Genetic evidence indicates that the orphan nuclear receptors estrogen receptor-related receptors...

View Full Study on PubMed →
In Vivo Study PubMed

An orally active estrogen receptor-related receptor agonist, SLU-PP-915, enhances aerobic exercise capacity.

The Journal of pharmacology and experimental therapeutics 2026
Billon C, Appourchaux K, Côté I et al.

Estrogen receptor-related receptors (ERRα, ERRβ, and ERRγ) are orphan nuclear receptors that regulate genes involved in mitochondrial biogenesis, oxidative phosphorylation, fatty acid oxidation, and the Krebs cycle. ERRs are essential for skeletal muscle adaptation to...

View Full Study on PubMed →
In Vitro Study PubMed

In Vitro Metabolism and Analytical Characterization of SLU-PP-332 and SLU-PP-915: Novel Pan-ERR Agonists With Doping Potential.

Rapid communications in mass spectrometry : RCM 2026
Möller T, Krug O, Thevis M et al.

Estrogen-related receptor (ERR) agonists such as the drug candidates SLU-PP-332 and SLU-PP-915 are currently being investigated as exercise mimetics, given their ability to trigger human physiological processes similar to those initiated by actual physical activity....

View Full Study on PubMed →
Mechanism Study PubMed

Chemical optimization of the exercise mimetic SLU-PP-332 enables insight into estrogen-related receptor signaling.

International journal of biological macromolecules 2026
Okda HE, Zhao P, Hayes M et al.

Estrogen-related receptors (ERRs) are master regulators of mitochondrial metabolism and exercise-responsive transcription, yet only a limited number of synthetic agonists with suitable potency and drug-like properties have been reported. SLU-PP-332 is a well-established exercise mimetic...

View Full Study on PubMed →
Research Notice: All studies are presented for educational and informational purposes only. These compounds are for in vitro laboratory research use only (RUO). Not for human or animal use. Not evaluated or approved by the FDA.
Compound Information

Technical Specifications

🔬 Molecular Profile

TypeNuclear Receptor Agonist
ClassificationSynthetic
Mol. Weight524.62 g/mol
FormulaC28H29FN4O3S
OriginSynthetic

🧊 Storage Requirements

❄️
Lyophilized (powder) -20°C up to 2 years
💉
Reconstituted 2-8°C up to 30 days
⏱️
Working solution Use within 24 hours
Protect from light • Avoid repeated freeze-thaw cycles
Research Grade

Research-Grade SLU-PP-332

≥98% purity, third-party COA verified, lyophilized for stability. For in vitro laboratory research use only.

⚠️ Research Use Only. Not for human or animal use. Not evaluated or approved by the FDA.

⚠️ Important Research Notice

All compounds listed are intended exclusively for in vitro laboratory research by qualified professionals. Not for human or animal consumption. Not approved by the FDA for any diagnostic, therapeutic, or clinical purpose. All research findings are sourced from peer-reviewed journals for educational reference only. Not to be interpreted as medical advice or product claims.